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Pamela Clark

Pamela Clark, CRNI, is an infusion nurse with the Houston Methodist Sugar Land Hospital.  She has more than 35 years of experience in infusion therapy and infusion education with both licensed nurses and patients. Her experience spans multiple infusion settings including: acute care, long-term care, home infusion, and ambulatory infusion care. She also has experience in oncology and oncology research.

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Class Accreditation

All states recognize our courses for accredited continuing nursing education, CNE, contact hours. This course is accredited by the following boards:
Provider approved by the California Board of Registered Nursing, Provider # CEP 15467.
Provider approved by the Arkansas, Florida, Georgia, New Mexico, North Dakota, South Carolina, and West Virginia Boards of Nursing through CE Broker, CE Provider #: 50-13256.  

The Use of Monoclonal Antibodies Against COVID-19

Contact Hours: 1
Cost: $10.00

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The Use of Monoclonal Antibodies Against COVID-19
The world is currently plagued by a pandemic that has affected more than one billion people and killed two million. Many believe that vaccines are the best hope for eventually eradicating this horrific disease but there are obstacles to achieving this goal in the very near future and there will be those for whom a vaccine is not the answer. Effective treatments are desperately needed in the short to midterm to prevent serious complications and death from the disease. Monoclonal antibodies are currently available to help meet that need but too few people, both health care professionals and the general public, know about this therapy. This course has been designed to provide the conceptual and operational knowledge to both promote this intervention and to educate the healthcare professional how to administer these medications safely and effectively. They are administered intravenously and State Boards of Nursing have varying positions on the role of the LPN/LVN in the administration of infusion therapy. Competency requirements are obtained and maintained through the nurse’s employer, facility or institution, skill checklists are provided for this within the course. 


Upon completion of this course, the participant will be able to:

  1. Describe the role of a monoclonal antibody in defending the body against COVID-19.
  2. Explain how a monoclonal antibody is produced for administration.
  3. List the patient qualifications required to receive one of the two monoclonal antibody products approved under the FDA EUA.
  4. Describe the preparation and administration procedures for the three monoclonal antibodies presented in the course.
  5. Recognize the different applications between the Eli Lilly and Regeneron products and tocilizumab in the treatment of COVID-19.


Chapter 1: Introduction to Monoclonal Antibodies

Chapter 2: How Monoclonal Antibodies Work

Chapter 3: Who Should Receive Monoclonal Antibodies

  • Bamlanivimab
  • Casirivimab and imdevimab
  • Tocilizumab

Chapter 4: Safe and Effective Administration

  • Preparation – bamlanivimab
  • Preparation – casirivimab and imdevimab
  • Administration – bamlanivimab and casirivimab/imdevimab
  • Tocilizumab (Actemra®)
    • Preparation
    • Administration
  • Patient/Parent/Caregiver Education

Chapter 5: Resources

Chapter 6: References